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Ask the Doctor: Low Testosterone

Content provided by the Faculty of the Harvard Medical School
Dr. LeWine

Howard LeWine, M.D., is chief editor of Internet Publishing at Harvard Health Publications. He is recognized as an outstanding clinician and teacher and is a recipient of the Internal Medicine Teacher of the Year award at Brigham and Women's Hospital. Dr. LeWine continues to practice Internal Medicine; most recently he became a hospitalist after practicing primary care for over 20 years.


I have been diagnosed with low testosterone. At what level do symptoms usually begin to appear?


The blood level of testosterone does not correlate with symptoms. A man can have a testosterone level below normal and feel absolutely fine.

Some symptoms of low testosterone include:

  • Decreased sexual desire

  • Erectile dysfunction

  • A depressed mood

  • Low energy level

  • Decreased muscle strength

However, these symptoms occur in many men. And most often, men with one or more of these symptoms have normal testosterone levels.

Because the symptoms can be subtle, I usually suggest a trial of testosterone replacement when a man has a low testosterone level. In addition to possibly making a man feel better, testosterone helps keep bones strong. Low testosterone contributes to osteoporosis in men.

There are potential risks to testosterone therapy. It stimulates the growth of normal prostate tissue and prostate cancer (if cancer already is present in the gland).

Last Annual Review Date: April 15, 2011 Copyright: Copyright by Harvard University. All rights reserved. Content Licensing by Belvoir Media Group
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