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Potentially Harmful Remedies for Migraines

By English, Stephanie
Content provided by: Better Medicine from Healthgrades

If you’ve ever taken an herbal remedy, you should know that some herbs may interact dangerously with migraine medicines. Although researchers need to do more studies, they advise people to use caution.

Triptans, prescription medications used to treat migraine pain, and tricyclic antidepressants, used to prevent migraine, may interact with the following herbal remedies:

  • Echinacea

  • Garlic (in large doses)

  • Ginkgo biloba

  • Ginseng

  • St. John’s wort

  • Valerian root

These herbs reduce the liver’s ability to process medicines. This may cause a dangerous interaction. For example, taking St. John’s wort with a tricyclic antidepressant can cause a serious—even fatal—reaction. Ginkgo biloba, ginseng, St. John’s wort and valerian root may worsen migraine symptoms. Other studies, however, show that St. John’s wort can lessen migraine pain.

More research about herb-drug interactions is needed. Because of the potentially dangerous effects, however, tell your health care provider and pharmacist about any herb, vitamin or other dietary supplement you take. Treat an herbal remedy just like a drug. If your provider and pharmacist know what herb you’re considering taking, they can advise you whether it is safe.

Medical Reviewer: [Akin, Louise RN, BSN, Chang, Alice MD, O'Brien, Chris RN, MPH, Sweetwood, Jane RN, MN, CCRN] Last Annual Review Date: 2012-06-06T00:00:00-06:00 Copyright: Copyright Health Ink & Vitality Communications

Reference: Migraine & Headaches section on Better Medicine


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